Cell proliferation within small intestinal crypts is the principal driving force for cell migration on villi

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Cell proliferation within small intestinal crypts is the principal driving force for cell migration on villi

The functional integrity of the intestinal epithelial barrier relies on tight coordination of cell proliferation and migration, with failure to regulate these processes resulting in disease. It is not known whether cell proliferation is sufficient to drive epithelial cell migration during homoeostatic turnover of the epithelium. Nor is it known precisely how villus cell migration is affected wh...

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2016

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fj.201601002